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Lombardi Research Lab

Lombardi Research Lab

Therapeutic peptides at biological barriers and interfaces

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Queen's University of Belfast

“Nothing in life is to be feared, it is only to be understood.
Now is the time to understand more, so that we may fear less.”

Marie Curie

Our Vision

The Lombardi Lab is building an interdisciplinary research programme focused on therapeutic peptides at biological barriers and interfaces. We are interested in how peptide structure, stability and interactions with biological environments influence transport, delivery and function. 

By combining peptide chemistry, drug delivery, human-relevant in vitro models and bioanalytical approaches, we aim to generate clearer experimental evidence on peptide behaviour and develop practical design principles for future peptide therapeutics and peptide-inspired systems.

Our Mission

Our mission is to create a rigorous and collaborative research environment where peptide science, barrier biology and bioengineering can be brought together to address difficult problems in therapeutic delivery and biological-interface function.

We are committed to training students and early-career researchers in careful experimental design, quantitative thinking, responsible research practice and interdisciplinary collaboration.

“Science is not only a disciple of reason,
but, also, one of romance and passion.”

Stephen Hawking

PI


Dr Lucia Lombardi is an Assistant Professor and Research Group Leader

Dept. Biological Science, Queen’s University Belfast

Dept. Chemical Engineering, Imperial College London

Meet the PI

Research


Current and developing areas include:

  • Therapeutic peptides at CNS-relevant barriers
  • Human-relevant engineered models for peptide evaluation
  • Peptide behaviour at mucosal and microbial interfaces
  • Peptide-regulated sensing systems
  • Design rules for peptide transport, delivery and function
Our research areas

Join us


We welcome enquiries from motivated students and researchers interested in peptide therapeutics, biological barriers, drug delivery, bioengineered models, mucosal and microbial interfaces, and peptide-regulated sensing systems.

Prospective MPhil, MRes, MSci, MSc and PhD students, as well as postdoctoral researchers interested in fellowship or externally funded opportunities, are encouraged to get in touch.

Opportunities

Latest News

  • AISUK 10th Anniversary Event with ESA Astronaut Samantha Cristoforetti

    AISUK 10th Anniversary Event with ESA Astronaut Samantha Cristoforetti

    AISUK – the Association of Italian Scientists in the UK – celebrated its 10th anniversary with a special event hosted at the Residence of the Ambassador of Italy in London. The event was organised by Lucia Lombardi, Co-Director of AISUK, in collaboration with the Embassy of Italy in London and…

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  • Congratulations, Angelina!!!

    Congratulations, Angelina!!!

    Our lab manager, Dr Angelina Madden, received the Queen’s Technician Award 2026 for Contribution to Sustainability. The award recognises exemplary actions to support the implementation of sustainability practices within the labs, and across wider University operations, teaching, and research.

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  • Sabanci University International Seed Collaboration Project

    Sabanci University International Seed Collaboration Project

    We are very grateful to Sabanci University for funding the project “AI-Guided Discovery and Validation of Human Blood–Brain Barrier Peptide Shuttles” that will now support the collaboration with Oznur Tastan and Nur Mustafaoglu. This is only the beginning, and we are sure we will do great things together. A special…

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  • Peptides: more than a trend

    Peptides: more than a trend

    Peptides are everywhere right now, yet many people still do not really know what they are. Until recently, peptides remained largely the language of scientists, discussed mainly in laboratories and specialist journals. Today, they appear in news headlines, in doctors’ offices, in skincare products, and even in everyday conversation. People…

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  • In conversation with the American Peptide Society

    In conversation with the American Peptide Society

    In her conversation with the American Peptide Society, Lucia shared a research vision that bridges peptide-based drug delivery across biological barriers with antimicrobial design against resistant pathogens.  At Queen’s University Belfast, she is building not just a lab, but a culture. One where scientific rigor and genuine human connection are…

    Read More…

Office and Lab

School of Biological Sciences
Queen's University Belfast
19 Chlorine Gardens
Belfast, BT9 5DL
United Kingdom

Other affiliation

Department of Chemical Engineering
Imperial College London
South Kensington Campus
London, SW7 2AZ
United Kingdom

Contacts

l.lombardi@qub.ac.uk
l.lombardi@imperial.ac.uk
+44 28 9097 1096

Lombardi Research Lab.

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